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Pomalidomide 4'-PEG3-azide

CAT: 0931-T39806-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T39806-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2271036-46-3
Target
E3 Ligase Ligand-Linker Conjugate
Related Pathways
PROTAC
Purity
0.9872
Bioactivity
Pomalidomide 4'-PEG3-azide is a chemically synthesized E3 ligase ligand-linker conjugate that incorporates the cereblon ligand derived from Pomalidomide, along with a linker. This compound is utilized in the synthesis of iRucaparib-TP3 (Compound 3), an effective PARP1 degrader developed through the PROTAC strategy and derived from Rucaparib.
Smiles
[N-]=[N+]=NCCOCCOCCOCCNC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3
Molecular Formula
C21H26N6O7
Molecular Weight
474.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C