ASP2453

CAT: 0931-T39738-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0931-T39738-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2241719-73-1

Target

Ras, ERK, Kras

Related Pathways

MAPK, GPCR/G Protein

Purity

0.9971

Bioactivity

ASP2453 is a potent, selective, and covalent inhibitor of KRAS G12C that inhibits the Son of Sevenless (SOS) -mediated interaction between KRAS G12C and Raf with an IC50 value of 40 nM.

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COCCCN1CCC(CC1)Oc1nc(N2CCC3(CN(C3)C(=O)C=C)CC2)c2cc(C3CC3)c(c(OCC(F)(F)F)c2n1)-c1c(C)ccc2[nH]ncc12

Molecular Formula

C40H48F3N7O4

Molecular Weight

747.85

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Related Products

Catalog	Name
T14334-01	ASP2535

Alternative Products

Catalog	Name
BA5785-1	ASP2453

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