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(3R,5S) -Fluvastatin

CAT: 0931-T39036Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T39036Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
155229-75-7
Target
Others, Autophagy, HMG-CoA Reductase
Related Pathways
Autophagy, Others, Metabolism
Bioactivity
(3R,5S) -Fluvastatin, the 3R,5S-isomer of Fluvastatin (XU 62-320 free acid), stands as the inaugural fully synthetic, competitive inhibitor of HMG-CoA reductase, exhibiting an IC50 value of 8 nM. It safeguards vascular smooth muscle cells from oxidative stress by activating the Nrf2-dependent antioxidant pathway.
Smiles
C(=C/[C@H](C[C@H](CC(O)=O)O)O)\C1=C(C=2C(N1C(C)C)=CC=CC2)C3=CC=C(F)C=C3
Molecular Formula
C24H26FNO4
Molecular Weight
411.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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