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Sibiromycin

CAT: 0931-T38673Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T38673Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
12684-33-2
Target
Others, DNA Alkylator/Crosslinker, Antibiotic
Related Pathways
DNA Damage/DNA Repair, Others, Microbiology/Virology
Bioactivity
Sibiromycin, a glycosylated pyrrolobenzodiazepines (PBDs) compound, is a naturally occurring and potent antitumor antibiotic. It exerts its activity by covalently binding to DNA in the minor groove at the NH2 of guanine.
Smiles
[H][C@@]12CC(\C=C\C)=CN1C(=O)c1cc(O[C@@H]3O[C@@H](C)[C@H](NC)[C@@](C)(O)[C@H]3O)c(C)c(O)c1N[C@@H]2O |c:6|
Molecular Formula
C24H33N3O7
Molecular Weight
475.542
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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