Alisertib Sodium

CAT: 0931-MF-0065109-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0065109-01Size:1 mg
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CAS Number
1028486-06-7
Target
Others|||Apoptosis|||Aurora Kinase|||Autophagy|||STAT
Related Pathways
Autophagy|||Chromatin/Epigenetic|||Others|||Apoptosis|||Cell Cycle/Checkpoint|||Stem Cells|||JAK/STAT signaling
Purity
0.9977
Bioactivity
Alisertib Sodium (MLN 8237 Sodium) is a selective Aurora A inhibitor that causes G2/M phase arrest and chromosomal misalignment, leading to tumour cell apoptosis, and can also inhibit STAT3 Tyr705 phosphorylation, resulting in downregulation of c-Myc expression.
Smiles
O=C(C1=CC=C(NC2=NC(C3=C(C(C4=C(OC)C=CC=C4F)=NC5)C=C(Cl)C=C3)=C5C=N2)C=C1OC)[O-].[Na+]
Molecular Formula
C27H19ClFN4NaO4
Molecular Weight
540.91
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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