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Alisertib Sodium

CAT: 0931-T38428-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T38428-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1028486-06-7
Target
Others, Apoptosis, Aurora Kinase, Autophagy, STAT
Related Pathways
Autophagy, Chromatin/Epigenetic, Others, Apoptosis, Cell Cycle/Checkpoint, Stem Cells, JAK/STAT signaling
Purity
0.9977
Bioactivity
Alisertib Sodium (MLN 8237 Sodium) is a selective Aurora A inhibitor that causes G2/M phase arrest and chromosomal misalignment, leading to tumour cell apoptosis, and can also inhibit STAT3 Tyr705 phosphorylation, resulting in downregulation of c-Myc expression.
Smiles
O=C(C1=CC=C(NC2=NC(C3=C(C(C4=C(OC)C=CC=C4F)=NC5)C=C(Cl)C=C3)=C5C=N2)C=C1OC)[O-].[Na+]
Molecular Formula
C27H19ClFN4NaO4
Molecular Weight
540.91
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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HY-10971AAlisertib (sodium)
MBS5799083Alisertib sodium
GTR19208152-01Alisertib sodium hydrate
MBS3600137-01Alisertib
MBS385561-01MLN8237 (Alisertib)
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C16135Alisertib (MLN8237)
HY-10971R-01Alisertib (Standard)

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