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Cryogenine

CAT: 0931-T38327-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T38327-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
10308-13-1
Target
Others, PGE Synthase
Related Pathways
Others, Immunology/Inflammation
Bioactivity
Cryogenine is an alkaloid originally isolated from H. salicifolia that exhibits anti-inflammatory activity. It inhibits prostaglandin synthetase (IC50 = 424 μM) and, at a dosage of 100 mg/kg per day (p.o.), reduces paw edema and the mean arthritic index in a rat model of adjuvant-induced polyarthritis.
Smiles
[H][C@]12C[C@@]3([H])CCCCN3[C@@]([H])(C1)c1cc(OC)c(OC)cc1-c1cc(ccc1O)\C=C/C(=O)O2 |c:34|
Molecular Formula
C26H29NO5
Molecular Weight
435.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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