JC-171

• Target :

  NOD-like Receptor (NLR) |||Others

• Related Pathways :

  Immunology/Inflammation|||Others

• Bioactivity :

  JC-171, a selective inhibitor of the NLRP3 inflammasome, effectively inhibits LPS/ATP-induced interleukin-1? (IL-1?) release from J774A.1 macrophages with an IC50 of 8.45 ?M[1].

• Smiles :

  COc1ccc(Cl)cc1C(=O)NCCc1ccc(cc1)S(=O)(=O)NO

• Molecular Formula :

  C16H17ClN2O5S

• Molecular Weight :

  384.83

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2112809-98-8