JC-171

• Target:

  NOD-like Receptor (NLR) |||Others

• Related Pathways:

  Immunology/Inflammation|||Others

• Bioactivity:

  JC-171, a selective inhibitor of the NLRP3 inflammasome, effectively inhibits LPS/ATP-induced interleukin-1? (IL-1?) release from J774A.1 macrophages with an IC50 of 8.45 ?M[1].

• Smiles:

  COc1ccc(Cl)cc1C(=O)NCCc1ccc(cc1)S(=O)(=O)NO

• Molecular Formula:

  C16H17ClN2O5S

• Molecular Weight:

  384.83

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2112809-98-8