JC-171

CAT: 0931-T38106-01Size: 1 mL - 10 mM (in DMSO)Dry Ice: NoHazardous: No

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CAT#:0931-T38106-01Size:1 mL - 10 mM (in DMSO)

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2112809-98-8

Target

NOD-like Receptor (NLR), Others

Related Pathways

Immunology/Inflammation, Others

Bioactivity

JC-171, a selective inhibitor of the NLRP3 inflammasome, effectively inhibits LPS/ATP-induced interleukin-1β (IL-1β) release from J774A.1 macrophages with an IC50 of 8.45 μM[1].

Smiles

COc1ccc(Cl)cc1C(=O)NCCc1ccc(cc1)S(=O)(=O)NO

Molecular Formula

C16H17ClN2O5S

Molecular Weight

384.83

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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