JC-171

CAT: 0931-T38106-01Size: 1 mL - 10 mM (in DMSO)Dry Ice: NoHazardous: No
CAT#:0931-T38106-01Size:1 mL - 10 mM (in DMSO)
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2112809-98-8
Target
NOD-like Receptor (NLR) |||Others
Related Pathways
Immunology/Inflammation|||Others
Bioactivity
JC-171, a selective inhibitor of the NLRP3 inflammasome, effectively inhibits LPS/ATP-induced interleukin-1? (IL-1?) release from J774A.1 macrophages with an IC50 of 8.45 ?M[1].
Smiles
COc1ccc(Cl)cc1C(=O)NCCc1ccc(cc1)S(=O)(=O)NO
Molecular Formula
C16H17ClN2O5S
Molecular Weight
384.83
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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