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Leukotriene C4 methyl ester

CAT: 0931-T37620-01Size: 25 µgDry Ice: NoHazardous: No
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CAT#:0931-T37620-01Size:25 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
73958-10-8
Target
Others, Endogenous Metabolite
Related Pathways
Others, Metabolism
Bioactivity
Leukotriene C4 (LTC4) is the parent cysteinyl-leukotriene produced by the LTC4 synthase-catalyzed conjugation of glutathione to LTA4. LTC4 is produced by neutrophils, macrophages, and mast cells, and by transcellular metabolism in platelets. It is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A) and exhibits potent smooth muscle contracting activity. LTC4-induced bronchoconstriction and enhanced vascular permeability contribute to the pathogenesis of asthma and acute allergic hypersensitivity. The concentration of LTC4 required to produce marked contractions of lung parenchymal strips and isolated tracheal rings is about 1 nM. LTC4 methyl ester is a more lipid soluble form of LTC4. The biological activity of LTC4 methyl ester has not been reported.
Smiles
CCCCC\C=C/C\C=C/C=C/C=C/[C@@H](SC[C@H](NC(=O)CC[C@H](N)C(O)=O)C(=O)NCC(O)=O)[C@@H](O)CCCC(=O)OC
Molecular Formula
C31H49N3O9S
Molecular Weight
639.81
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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Alternative Products

CatalogName
IDA85138Leukotriene A3 methyl ester
HY-W747562Leukotriene A 3 methyl ester
MBS5785241Leukotriene C4 methyl ester
sc-221848ALeukotriene E4 methyl ester
BML-LA004-0050Leukotriene A4 methyl ester
sc-221846ALeukotriene D4 methyl ester
453937-01LTA4 (Leukotriene A4 methyl ester)
sc-200490LTA3 (Leukotriene A3 methyl ester)
sc-221842ALeukotriene A4-d5 methyl ester
HY-126716SLeukotriene C4-d5 methyl ester

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