Bimatoprost methyl ester

• Target:

  Others

• Related Pathways:

  Others

• Bioactivity:

  Prostaglandin F2? (PGF2?) drives luteolysis and smooth muscle contraction by activating the FP receptor. Bimatoprost methyl ester is a lipophilic analog of 17-phenyl trinor PGF2?, a potent agonist for the FP receptor. 17-phenyl trinor PGF2? binds the FP receptor on ovine luteal cells with a relative potency of 756% compared to that of PGF2?. Esters of PGs serve as prodrugs, as they are efficiently hydrolyzed in certain tissues to generate the bioactive free acid.

• Smiles:

  COC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\[C@@H](O)CCc1ccccc1

• Molecular Formula:

  C24H34O5

• Molecular Weight:

  402.531

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  38315-47-8