(rel) -Asperparaline A

CAT: 0931-MF-0000675-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0000675-01Size:1 mg
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CAS Number
195966-93-9
Target
Others|||AChR
Related Pathways
Neuroscience|||Others
Bioactivity
Aspergillimide is a fungal metabolite originally isolated from A. japonicus.1 It reduces nicotinic acetylcholine receptor (nAChR) peak and slowly-desensitizing amplitudes induced by acetylcholine in silkworm (B. mori) larval neurons (IC50s = 20.2 and 39.6 nM, respectively) but has no effect on chicken ?3?4-, ?4?2-, and ?7-containing nAChRs.2 Dietary administration of aspergillimide A (10 ?g/g of diet) induces paralysis in silkworm fourth instar larvae.1 Aspergillimide A (10 and 20 mg/kg) reduces T. colubriformis fecal egg count in gerbils.3
Smiles
[H][C@@]12C[C@]34[C@@H](C)CCN3C[C@@]1(C[C@]1(CC(=O)N(C)C1=O)C2(C)C)N(C)C4=O|TLB:20:1:8.9:23.25|
Molecular Formula
C20H29N3O3
Molecular Weight
359.47
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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