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Z-LLL-AMC

CAT: 0931-T37418Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T37418Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
152015-61-7
Target
Proteasome
Related Pathways
Proteases/Proteasome, Ubiquitination
Bioactivity
Z-LLL-AMC is a fluorogenic substrate for the chymotrypsin-like activity of the 26S proteasome or 20S proteolytic core. Chymotrypsin-like activity can be quantified by fluorescent detection of free AMC (also known as 7-amino-4-methylcoumarin), which is excited at 340-360 nm and emits at 440-460 nm. Z-LLL-AMC is typically used in cell lysates after experimental treatment.
Smiles
CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)Nc1ccc2c(C)cc(=O)oc2c1
Molecular Formula
C36H48N4O7
Molecular Weight
648.801
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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