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Stemazole

CAT: 0804-HY-116057-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-116057-01Size:1 mg
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Description
Stemazole is a protective agent that promotes stem cell survival. Stemazole has the protective effect of human embryonic stem cells (hESCs) . Stemazole enhances clonal expansion of single cells and decreases apoptosis. Stemazole for the study of stem cell survival in starvation culture [1].
CAS Number
317337-07-8
Product Name Alternative
Carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/stemazole.html
Purity
99.96
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
SC1=NN=C(O1)C2=CC=C(C=C2)NC(NN)=S
Molecular Formula
C9H9N5OS2
Molecular Weight
267.34
Precautions
H302, H315, H319, H335
References & Citations
[1]Sun Y, et al. Stemazole promotes survival and preserves stemness in human embryonic stem cells. FEBS J. 2018 Feb;285 (3) :531-541.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

N-(4-(5-Mercapto-1,3,4-oxadiazol-2-yl)phenyl)hydrazinecarbothioamide
CAS Number317337-07-8
PubChem CID3876544
IUPAC Name1-amino-3-[4-(2-sulfanylidene-3H-1,3,4-oxadiazol-5-yl)phenyl]thiourea
Molecular FormulaC9H9N5OS2
Molecular Weight267.3
XLogP0.9
Topological Polar Surface Area148
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count5
Rotatable Bond Count2
Heavy Atom Count17
Formal Charge0
Complexity351
SMILES
C1=CC(=CC=C1C2=NNC(=S)O2)NC(=S)NN
InChI
InChI=1S/C9H9N5OS2/c10-12-8(16)11-6-3-1-5(2-4-6)7-13-14-9(17)15-7/h1-4H,10H2,(H,14,17)(H2,11,12,16)
InChIKey
DSZWZHYEFYRNQI-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of N-(4-(5-Mercapto-1,3,4-oxadiazol-2-yl)phenyl)hydrazinecarbothioamide
CAS: 317337-07-8
CID: 3876544
Formula: C9H9N5OS2
MW: 267.3
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight267.3
XLogP30.9
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count5
Rotatable Bond Count2
Exact Mass267.02485227
Monoisotopic Mass267.02485227
Topological Polar Surface Area148 Ų
Heavy Atom Count17
Formal Charge0
Complexity351
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
MBS5778536Stemazole

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