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Stemazole

CAT: 0931-T28866-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T28866-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
317337-07-8
Target
Others, Apoptosis
Related Pathways
Apoptosis, Others
Purity
0.9859
Bioactivity
Stemazole is a novel small molecule human stem/progenitor cell proliferation activator that promotes the survival of human embryonic stem cells and maintains stemness, and promotes the survival of oligodendrocyte precursor cells in vitro. Stemazole significantly increased cell survival and clone formation in a dose-dependent manner, reduced apoptosis, and promoted recovery of motor dysfunction and myelin repair. Stemazole can be used as a therapeutic agent in demyelinating disorders, promoting OPC survival in vitro and regeneration in vivo.
Smiles
S=C1OC(C2=CC=C(NC(NN)=S)C=C2)=NN1
Molecular Formula
C9H9N5OS2
Molecular Weight
267.33
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

N-(4-(5-Mercapto-1,3,4-oxadiazol-2-yl)phenyl)hydrazinecarbothioamide
CAS Number317337-07-8
PubChem CID3876544
IUPAC Name1-amino-3-[4-(2-sulfanylidene-3H-1,3,4-oxadiazol-5-yl)phenyl]thiourea
Molecular FormulaC9H9N5OS2
Molecular Weight267.3
XLogP0.9
Topological Polar Surface Area148
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count5
Rotatable Bond Count2
Heavy Atom Count17
Formal Charge0
Complexity351
SMILES
C1=CC(=CC=C1C2=NNC(=S)O2)NC(=S)NN
InChI
InChI=1S/C9H9N5OS2/c10-12-8(16)11-6-3-1-5(2-4-6)7-13-14-9(17)15-7/h1-4H,10H2,(H,14,17)(H2,11,12,16)
InChIKey
DSZWZHYEFYRNQI-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of N-(4-(5-Mercapto-1,3,4-oxadiazol-2-yl)phenyl)hydrazinecarbothioamide
CAS: 317337-07-8
CID: 3876544
Formula: C9H9N5OS2
MW: 267.3
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight267.3
XLogP30.9
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count5
Rotatable Bond Count2
Exact Mass267.02485227
Monoisotopic Mass267.02485227
Topological Polar Surface Area148 Ų
Heavy Atom Count17
Formal Charge0
Complexity351
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
MBS5778536Stemazole

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