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Rolapitant hydrochloride

CAT: 0931-T3724-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T3724-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
858102-79-1
Target
Neurokinin receptor
Related Pathways
Neuroscience, GPCR/G Protein
Purity
0.9979
Bioactivity
Rolapitant (SCH619734) hydrochloride is a potent, selective, long-acting, and orally active neurokinin 1 (NK1) receptor antagonist with a K_i of 0.66 nM, which does not interact with CYP3A4 and demonstrates potent centrally-mediated anti-emetic activity in both acute and delayed ferret emesis models [1] [2].
Smiles
Cl.C[C@@H](OC[C@]1(CC[C@]2(CCC(=O)N2)CN1)c1ccccc1)c1cc(cc(c1)C(F)(F)F)C(F)(F)F
Molecular Formula
C25H27ClF6N2O2
Molecular Weight
536.94
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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