Bilaid C

• Target :

  Opioid Receptor

• Related Pathways :

  Neuroscience|||Endocrinology/Hormones|||GPCR/G Protein

• Bioactivity :

  Bilaid C is a tetrapeptide ?-opioid receptor agonist (Ki= 210 nM in HEK293 cell membranes expressing the human receptor) that has been found inPenicillium.1It inhibits forskolin-induced cAMP accumulation by 77% in HEK293 cells expressing the human ?-opioid receptor when used at a concentration of 10 ?M. Bilaid C induces inward rectifying potassium channel (Kir) currents in rat locus coeruleus slices that endogenously express high levels of the ?-opioid receptor (EC50= 4.2 ?M) .

• Smiles :

  CC(C)[C@H](NC(=O)[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)N[C@H](Cc1ccccc1)C(O)=O

• Molecular Formula :

  C28H38N4O6

• Molecular Weight :

  526.62

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2393866-13-0