Terpendole C

CAT: 0931-T36776-01Size: 500 µgDry Ice: NoHazardous: No
CAT#:0931-T36776-01Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
156967-65-6
Target
Others|||Acyltransferase
Related Pathways
Metabolism|||Others
Bioactivity
Terpendole C is an indole diterpene alkaloid fungal metabolite originally isolated from A. yamanashiensis and an inhibitor of acyl-coenzyme A:cholesterol acyltransferase (ACAT; IC50 = 2.1 ?M in rat liver microsomes) . It also inhibits ACAT in J774 macrophages (IC50 = 0.46 ?M) without affecting cell growth.
Smiles
[H][C@]12O[C@@]11[C@]([H])(CC[C@]3(C)[C@@]4(C)c5[nH]c6ccccc6c5C[C@]4([H])CC[C@@]13O)O[C@@]1([H])[C@@]2([H])O[C@@H](OC1(C)C)C=C(C)C|wU:8.9,22.26,31.38,1.0,wD:26.32,3.2,10.11,4.5,34.46,29.35,(2.12,.37,;2.78,1.76,;4.17,1.1,;4.05,2.63,;3.93,4.17,;3.8,5.7,;5.19,5.04,;6.58,4.38,;6.71,2.85,;7.98,3.72,;8.1,2.19,;8.61,3.64,;9.52,2.78,;10.32,4.1,;11.82,3.74,;13.09,4.61,;14.48,3.95,;14.6,2.42,;13.34,1.55,;11.95,2.21,;10.52,1.61,;9.72,.3,;8.22,.65,;8.51,-.86,;6.96,-.22,;5.57,.44,;5.44,1.97,;4.93,.52,;2.53,4.83,;1.27,3.95,;1.14,5.49,;1.39,2.42,;1.52,.88,;.12,1.55,;-1.27,2.21,;-1.39,3.74,;-.12,4.61,;-1.21,5.71,;.77,5.87,;-2.53,1.33,;-3.93,1.99,;-5.19,1.12,;-4.05,3.53,)|
Molecular Formula
C32H41NO5
Molecular Weight
519.682
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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