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Mollugin

CAT: 0931-T3673-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T3673-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
55481-88-4
Target
ROS, Reactive Oxygen Species, c-Myc, NF-κB, Apoptosis, VEGFR, HER, JAK
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis, Metabolism, Immunology/Inflammation, NF-κB, JAK/STAT signaling, Cell Cycle/Checkpoint, Apoptosis, Chromatin/Epigenetic, Stem Cells
Purity
0.9987
Bioactivity
Mollugin (Rubimaillin) may be a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway. Mollugin as a candidate for a chemotherapeutic agent in OSCCs via the upregulation of the HO-1 and Nrf2 pathways and the downregulation of NF- κ B. Mollugin may be a novel therapeutic candidate for bone loss-associated disorders including osteoporosis, rheumatoid arthritis, and periodontitis. Also, it has anticancer efficacy, can modulate the HER2 pathway in HER2-overexpressing Y cells with a potential role in the treatment and prevention of human breast and ovarian Y with HER2 overexpression.
Smiles
COC(=O)c1c(O)c2ccccc2c2OC(C)(C)C=Cc12
Molecular Formula
C17H16O4
Molecular Weight
284.31
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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