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Bottromycin A2

CAT: 0931-T36706Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T36706Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
15005-62-6
Target
Others, Antibacterial, Antibiotic
Related Pathways
Others, Microbiology/Virology
Bioactivity
Bottromycin A2is an antibiotic originally isolated fromStreptomyces.1It blocks the binding of aminoacyl-tRNA to the A site of the 50S ribosome, inhibiting protein synthesis.2Bottromycin A2is active against clinical isolates of methicillin-resistantStaphylococcus aureus (MRSA) and vancomycin-resistantEnterococciwith MIC values of 1 and 0.5 μg/ml, respectively.
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[H][C@@]12[C@H](C)CCN1C(=O)CN=C(N[C@H](C(=O)N[C@@H]([C@@H](C)c1ccccc1)C(=O)N[C@H](CC(=O)OC)c1nccs1)C(C)(C)C)C(NC(=O)C(NC2=O)C(C)C)C(C)(C)C |w:10.10,@:52,@@:55|
Molecular Formula
C42H62N8O7S
Molecular Weight
823.07
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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CatalogName
MBS5802546Bottromycin A2

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