USP30 inhibitor 18

CAT: 0931-T36682-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0931-T36682-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2242582-40-5

Target

DUB, Mitophagy

Related Pathways

Autophagy, DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Ubiquitination

Purity

0.9985

Bioactivity

USP30 inhibitor 18 is a selective inhibitor of USP30 (IC50 = 0.02 μM) . USP30 inhibitor 18 is able to accelerate mitophagy and increase protein ubiquitination.

Smiles

CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)[C@H](Cc2ccccc2)NC(=O)c2ccc(F)cc2)cc1

Molecular Formula

C26H28FN3O4S

Molecular Weight

497.58

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Chemical Information

USP30 inhibitor 18

CAS Number	2242582-40-5
PubChem CID	142474792
IUPAC Name	N-[(2S)-1-[4-(tert-butylsulfamoyl)anilino]-1-oxo-3-phenylpropan-2-yl]-4-fluorobenzamide
Molecular Formula	C26H28FN3O4S
Molecular Weight	497.6
XLogP	4.1
Topological Polar Surface Area	113
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	9
Heavy Atom Count	35
Formal Charge	0
Complexity	801

SMILES

CC(C)(C)NS(=O)(=O)C1=CC=C(C=C1)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)C3=CC=C(C=C3)F

InChI

InChI=1S/C26H28FN3O4S/c1-26(2,3)30-35(33,34)22-15-13-21(14-16-22)28-25(32)23(17-18-7-5-4-6-8-18)29-24(31)19-9-11-20(27)12-10-19/h4-16,23,30H,17H2,1-3H3,(H,28,32)(H,29,31)/t23-/m0/s1

InChIKey

NRHPFMQPXSSELC-QHCPKHFHSA-N

Chemical Structure

2D Structure

CAS: 2242582-40-5

CID: 142474792

Formula: C26H28FN3O4S

MW: 497.6

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	497.6
XLogP3	4.1
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	9
Exact Mass	497.17845572
Monoisotopic Mass	497.17845572
Topological Polar Surface Area	113 Å²
Heavy Atom Count	35
Formal Charge	0
Complexity	801
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

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T61472-01	Tubulin inhibitor 18
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Alternative Products

Catalog	Name
BUP04659-01	USP30 inhibitor 11
GTR19171020-01	USP30 inhibitor 18
339181	USP30
70R-8855	USP30 antibody
346434-01	USP30 discontinued
DF4590-BP	USP30 Peptide
UA080241-01	USP30 Protein

USP30 inhibitor 18

Chemical Information

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