Products for Research Use Only
RegisterLogin

Quazinone

CAT: 0931-T36547-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T36547-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
70018-51-8
Target
Others, MAPK, PDE
Related Pathways
Others, MAPK, Metabolism
Bioactivity
Quazinone is a selective inhibitor of phosphodiesterase 3 (PDE3) with positive inotropic and vasodilating properties. It induces relaxation of precontracted isolated human cavernous smooth muscle (IC50 = 4.2 μM), increases myocardial contractile force in anesthetized open-chest dogs in a dose-dependent manner (10-300 μg/kg), decreases systolic and diastolic blood pressure, and inhibits DNA synthesis induced by the PDGF isoform PDGF-BB in bovine coronary artery smooth muscle cells in a concentration-dependent manner.
Smiles
C[C@H]1N2C(NC=3C(C2)=C(Cl)C=CC3)=NC1=O
Molecular Formula
C11H10ClN3O
Molecular Weight
235.67
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
MBS5797660Quazinone
463329-01Quazinone (Ro 13-6438)
bs-82038C-01Ro 13-6438 (Quazinone)

Popular Products