SP 10

• Target:

  Cholinesterase (ChE)

• Related Pathways:

  Neuroscience

• Bioactivity:

  Peptide originally derived from SARS-CoV Spike (S) protein; corresponds to amino acid residues 668 to 679. Highly potent inhibitor of SARS-CoV S protein and ACE2 interaction (IC50 = 1.88 nM in biochemical assay) . Inhibits interaction of SARS-CoV S protein and Vero E6 cells in vitro. Please note, this peptide displays 80% sequence identity to homologous site on SARS-CoV-2 S-protein (residues 689-697) .

• Smiles:

  CC[C@H] (C) [C@H] (NC (=O) [C@H] (CO) NC (=O) [C@H] (CCCCN) NC (=O) [C@H] (CCC (N) =O) NC (=O) [C@H] (CO) NC (=O) [C@@H] (NC (=O) [C@@H] (N) CO) [C@@H] (C) O) C (=O) N[C@@H] (C (C) C) C (=O) N[C@@H] (C) C (=O) N[C@@H] (Cc1ccc (O) cc1) C (=O) N[C@@H] ([C@@H] (C) O) C (=O) N[C@@H] (CCSC) C (O) =O |@@:53|

• Molecular Formula:

  C56H94N14O20S

• Molecular Weight:

  1315.51

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  882157-88-2