SP-96

• Target:

  Aurora Kinase

• Related Pathways:

  Cell Cycle/Checkpoint|||Chromatin/Epigenetic

• Purity:

  0.9954

• Bioactivity:

  SP-96 is a highly effective and selective inhibitor of Aurora B with an IC50 of 0.316 nM. SP-96 shows selective growth inhibition in NCI60 screening, including MDA-MD-468 (GI50=107 nM) . SP-96 can be used in triple negative breast cancer studies.

• Smiles:

  Cn1cc(cn1)-c1ccc2c(Nc3cccc(NC(=O)Nc4cccc(F)c4)c3)ncnc2c1

• Molecular Formula:

  C25H20FN7O

• Molecular Weight:

  453.47

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2682114-54-9