TAN 420E

CAT: 0931-T36397Size: 500 µgDry Ice: NoHazardous: No

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CAT#:0931-T36397Size:500 µg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

91700-93-5

Target

Others, ROS, Antibiotic

Related Pathways

Others, Immunology/Inflammation, Microbiology/Virology

Bioactivity

TAN 420E is a bacterial metabolite originally isolated from Streptomyces. It scavenges 2,2-diphenyl-1-picrylhydrazyl radicals in a cell-free assay (IC50 = 1.3 μM) and reduces thiobarbituric acid reactive substances (TBARS) in rat liver microsomes by 72% when used at a concentration of 100 μg/ml. TAN 420E is active against B. brevis, B. cereus, M. flavus, and S. aureus (MICs = 50-100 μg/ml) . It is cytotoxic to P388 and KB lymphocytic leukemia cells (EC50s = 0.022 and 0.3 μg/ml, respectively) .

Smiles

CO[C@H]1C[C@H](C)[C@@H](OC)c2cc(O)cc(NC(=O)\C(C)=C/C=C/[C@H](OC)[C@@H](OC(N)=O)\C(C)=C\[C@H](C)[C@H]1OC)c2O |c:19,t:21,32|

Molecular Formula

C30H44N2O9

Molecular Weight

576.687

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Catalog	Name
HY-W747504-01	TAN-420E
T068-2.5MG	TAN 420E
441624-01	Antibiotic TAN 420E
MBS651450-01	Herbimycin A, dihydro- (Antibiotic TAN 420E, Antibiotic NK 86-0084)

TAN 420E

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