SM-1295

• Target:

  Apoptosis|||Others|||IAP

• Related Pathways:

  Others|||Apoptosis

• Bioactivity:

  SM-1295 serves as an antagonist to the inhibitor of apoptosis protein (IAP), demonstrating dissociation constant (Kd) values of 3077 nM for XIAP-BIR3, 3.2 nM for c-IAP1-BIR3, and 9.5 nM for c-IAP2-BIR3, respectively[1][2].

• Smiles:

  [H][C@]12CC[C@H](N1C(=O)[C@H](CN(CC2)C(=O)Cc1ccccc1)NC(=O)[C@H](C)NC)C(=O)NCc1ccc(Br)cc1

• Molecular Formula:

  C29H36BrN5O4

• Molecular Weight:

  598.53

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1562375-46-5