16 (S) -Iloprost

CAT: 0931-T36212-01Size: 500 µgDry Ice: NoHazardous: No

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CAT#:0931-T36212-01Size:500 µg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

74843-14-4

Target

Prostaglandin Receptor, Others

Related Pathways

GPCR/G Protein, Others, Immunology/Inflammation

Bioactivity

Iloprost is a second generation structural analog of prostacyclin (PGI2) with about ten-fold greater potency than the first generation stable analogs, typified by carbaprostacyclin. Iloprost binds with equal affinity to the recombinant human IP and EP1 receptors with a Ki value of 11 nM. Most preparations of iloprost contain 16 (S) and 16 (R) stereoisomers. 16 (S) -Iloprost potently inhibits platelet aggregation with an IC50 value of 3.5 nM.

Smiles

C(=C/[C@H]([C@H](CC#CC)C)O)\[C@@H]1[C@@]2([C@@](C/C(=C\CCCC(O)=O)/C2)(C[C@H]1O)[H])[H]

Molecular Formula

C22H32O4

Molecular Weight

360.49

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Alternative Products

Catalog	Name
B6933-1	Iloprost
HY-A0096A	(Z) -Iloprost
A15951-25	Iloprost 25mg
A15951-1	Iloprost 1mg
HY-A0096R	Iloprost (Standard)
HY-A0096S-01	Iloprost-d4

16 (S) -Iloprost

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