Avenanthramide-C methyl ester

CAT: 0931-T36198-01Size: 500 µgDry Ice: NoHazardous: No
CAT#:0931-T36198-01Size:500 µg
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CAS Number
955382-52-2
Target
NF-?B|||Others
Related Pathways
NF-?B|||Others
Bioactivity
Avenanthramide-C methyl ester inhibits NF-?B activation by blocking the phosphorylation of IKK and I?B (IC50 ~ 40 ?M), thereby dose-dependently inhibiting the expression and secretion of IL-6, IL-8, and MCP-1 in human aortic endothelial cells.
Smiles
C(OC)(=O)C1=C(NC(/C=C/C2=CC(O)=C(O)C=C2)=O)C=CC(O)=C1
Molecular Formula
C17H15NO6
Molecular Weight
329.3
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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