Avenanthramide-C methyl ester

• Target :

  NF-?B|||Others

• Related Pathways :

  NF-?B|||Others

• Bioactivity :

  Avenanthramide-C methyl ester inhibits NF-?B activation by blocking the phosphorylation of IKK and I?B (IC50 ~ 40 ?M), thereby dose-dependently inhibiting the expression and secretion of IL-6, IL-8, and MCP-1 in human aortic endothelial cells.

• Smiles :

  C(OC)(=O)C1=C(NC(/C=C/C2=CC(O)=C(O)C=C2)=O)C=CC(O)=C1

• Molecular Formula :

  C17H15NO6

• Molecular Weight :

  329.3

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  955382-52-2