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Avenanthramide-C methyl ester

CAT: 0931-T36198-01Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0931-T36198-01Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
955382-52-2
Target
NF-κB, Others
Related Pathways
NF-κB, Others
Bioactivity
Avenanthramide-C methyl ester inhibits NF-κB activation by blocking the phosphorylation of IKK and IκB (IC50 ~ 40 μM), thereby dose-dependently inhibiting the expression and secretion of IL-6, IL-8, and MCP-1 in human aortic endothelial cells.
Smiles
C(OC)(=O)C1=C(NC(/C=C/C2=CC(O)=C(O)C=C2)=O)C=CC(O)=C1
Molecular Formula
C17H15NO6
Molecular Weight
329.3
Shipping Conditions
Ice Packs
Storage Temperature
-20°C