Flumequine-13C3

• Target :

  Topoisomerase|||Antibacterial|||Antibiotic

• Related Pathways :

  Microbiology/Virology|||DNA Damage/DNA Repair

• Bioactivity :

  Flumequine-13C3is intended for use as an internal standard for the quantification of flumequine by GC- or LC-MS. Flumequine is a fluoroquinolone antibiotic.1It is active againstS. aureus, S. pyogenes, B. subtilis, E. coli, P. aeruginosa, S. faecalis, andK. pneumoniae (MICs = 1-100 ?g/ml) . Flumequine is also active against field isolates of B. hyodysenteriae (MICs = 6.25-200 ?g/ml) .2It inhibits DNA gyrase, disrupting supercoiling of bacterial DNA to block transcription and replication.3

• Smiles :

  CC1CCc2cc(F)cc3c2n1c[13c]([13C](O)=O)[13c]3=O

• Molecular Formula :

  C14H12FNO3

• Molecular Weight :

  264.229

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1185049-09-5