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Nebentan

CAT: 0931-T36007-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T36007-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
403604-85-3
Target
Others, Endothelin Receptor
Related Pathways
GPCR/G Protein, Others
Bioactivity
Nebentan (YM598) is a potent, selective and orally active non-peptide endothelin ETA receptor antagonist through the modification of Bosentan . Nebentan inhibits [125I] endothelin-1 binding to cloned human endothelin ETA and ETB receptor, with Ki of 0.697 nM and 569 nM, respectively[1]. YM598 can ameliorate the progression of cor pulmonale and myocardial infarction in vivo[2].
Smiles
COc1ccccc1Oc1c(NS(=O)(=O)\C=C\c2ccccc2)nc(nc1OC)-c1ncccn1
Molecular Formula
C24H21N5O5S
Molecular Weight
491.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
DRA60485-01Nebentan
HY-106994A-01Nebentan (potassium)
578048Nebentan potassium

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