Ent-Prostaglandin E2

• Target :

  Others|||Prostaglandin Receptor

• Related Pathways :

  GPCR/G Protein|||Immunology/Inflammation|||Others

• Bioactivity :

  Enzymatically-derived prostaglandin E2 (PGE2) is an optically pure compound whereas PGE2 derived from the free radical-catalyzed peroxidation of arachidonate is a racemic mixture. Ent-PGE2 is the opposite enantiomer of PGE2. Significant amounts of racemic PGE2 (rac-PGE2) are generated in vitro and in vivo in settings of oxidative stress via the isoprostane pathway. A proposed mechanism for the formation of rac-PGE2 involves the base catalyzed equilibration from 15-E2t-isoprostane (8-iso-PGE2), generated from the 15-H2t-isoprostane endoperoxide.

• Smiles :

  CCCCC[C@@H](O)\C=C\[C@@H]1[C@@H](O)CC(=O)[C@H]1C\C=C/CCCC(O)=O

• Molecular Formula :

  C20H32O5

• Molecular Weight :

  352.471

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  65085-69-0