Paraherquamide A

• Target :

  Others

• Related Pathways :

  Others

• Bioactivity :

  Paraherquamide A is a mycotoxin anthelmintic originally isolated from P. paraherquei. It binds to acetylcholine receptors (IC50 = 0.5 nM for head homogenates of M. domestica) and acts as an antagonist. Paraherquamide A is toxic to C. elegans (LD50 = 2.5 ?g/ml) and effective against T. colubriformis infection in gerbils when used at doses ranging from 0.39 to 200 mg/kg. It is toxic to mice (LD50 = 14.9 mg/kg) .

• Smiles :

  CN1C(=O)[C@]23C[C@H]4C(C)(C)[C@@]5(C[C@]14CN2CC[C@@]3(C)O)C(=O)Nc1c5ccc2OC(C)(C)C=COc12

• Molecular Formula :

  C28H35N3O5

• Molecular Weight :

  493.604

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  77392-58-6