CC-90005

CAT: 0931-T35829-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T35829-01Size:25 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1799574-70-1

Target

Others, PKC

Related Pathways

Chromatin/Epigenetic, Others, Cytoskeletal Signaling

Bioactivity

CC-90005 is a potent, selective, and orally active inhibitor of protein kinase C-θ (PKC-θ) with an IC50 of 8 nM, demonstrating strong selectivity over PKC-δ (IC50=4440 nM) . Additionally, CC-90005 can inhibit T cell activation by IL-2 expression[1].

Smiles

CC(F)(F)COc1ncncc1CNc1ncc(C#N)c(N[C@@H]2CC[C@H](O)C(C)(C)C2)n1

Molecular Formula

C21H27F2N7O2

Molecular Weight

447.48

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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BA6460-100	CC-90001
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CC-90005

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