CC-90005

• Target:

  Others|||PKC

• Related Pathways:

  Chromatin/Epigenetic|||Others|||Cytoskeletal Signaling

• Bioactivity:

  CC-90005 is a potent, selective, and orally active inhibitor of protein kinase C-? (PKC-?) with an IC50 of 8 nM, demonstrating strong selectivity over PKC-? (IC50=4440 nM) . Additionally, CC-90005 can inhibit T cell activation by IL-2 expression[1].

• Smiles:

  CC(F)(F)COc1ncncc1CNc1ncc(C#N)c(N[C@@H]2CC[C@H](O)C(C)(C)C2)n1

• Molecular Formula:

  C21H27F2N7O2

• Molecular Weight:

  447.48

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1799574-70-1