Destruxin B2

• Target :

  Others|||HBV

• Related Pathways :

  Microbiology/Virology|||Others

• Bioactivity :

  Destruxin B2 is a cyclic hexadepsipeptide mycotoxin that has been found in M. anisopliae and has antiviral, insecticidal, and phytotoxic activities.1,2,3 It inhibits secretion of hepatitis B virus surface antigen (HBsAg) by Hep3B cells expressing hepatitis B virus (HBV) DNA (IC50 = 1.3 ?M) .1 Destruxin B2 is toxic to Sf9 insect cells in an electric cell-substrate impedance sensing (ECIS) test with a 50% inhibitory concentration (ECIS50) value of 92 ?M.4 It is also phytotoxic to B. napus leaves.3

• Smiles :

  [H][C@@]12CCCN1C(=O)[C@@H](CC(C)C)OC(=O)CCNC(=O)[C@H](C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@@H](NC2=O)C(C)C

• Molecular Formula :

  C29H49N5O7

• Molecular Weight :

  579.739

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  79386-00-8