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Destruxin B2

CAT: 0931-T35771Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T35771Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
79386-00-8
Target
Others, HBV
Related Pathways
Microbiology/Virology, Others
Bioactivity
Destruxin B2 is a cyclic hexadepsipeptide mycotoxin that has been found in M. anisopliae and has antiviral, insecticidal, and phytotoxic activities.1,2,3 It inhibits secretion of hepatitis B virus surface antigen (HBsAg) by Hep3B cells expressing hepatitis B virus (HBV) DNA (IC50 = 1.3 μM) .1 Destruxin B2 is toxic to Sf9 insect cells in an electric cell-substrate impedance sensing (ECIS) test with a 50% inhibitory concentration (ECIS50) value of 92 μM.4 It is also phytotoxic to B. napus leaves.3
Smiles
[H][C@@]12CCCN1C(=O)[C@@H](CC(C)C)OC(=O)CCNC(=O)[C@H](C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@@H](NC2=O)C(C)C
Molecular Formula
C29H49N5O7
Molecular Weight
579.739
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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