T2AA

CAT: 0931-T35719-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0931-T35719-01Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1380782-27-3

Target

DNA/RNA Synthesis

Related Pathways

Cell Cycle/Checkpoint, DNA Damage/DNA Repair

Purity

0.9953

Bioactivity

T2AA (4-[4-[ (2S) -2-amino-3-hydroxypropyl]-2,6-diiodophenoxy]phenol) is an inhibitor of proliferating cell nuclear antigen (PCNA) with IC50 of 1 μM for PCNA/PIP-box peptide interaction. T2AA suppresses cancer cell growth and causes DNA replication stress by stalling DNA replication forks and inhibiting PCNA interaction with DNA polymerase δ.

Smiles

N[C@H](CO)Cc1cc(I)c(Oc2ccc(O)cc2)c(I)c1

Molecular Formula

C15H15I2NO3

Molecular Weight

511.09

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Alternative Products

Catalog	Name
BA3993-10	T2AA
FFC78227-01	T2AA hydrochloride
HY-110111A-01	T2AA (hydrochloride)

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