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4-oxo-2-Nonenal

CAT: 0931-T35646-01Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0931-T35646-01Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
103560-62-9
Target
Others, TRP/TRPV Channel
Related Pathways
Membrane transporter/Ion channel, Others
Bioactivity
4-hydroxy Nonenal is a lipid peroxidation product derived from oxidized ω-6 polyunsaturated fatty acids such as arachidonic acid and linoleic acid. [1] [2] It exhibits various biological activities such as cytotoxicity, growth inhibiting activity, genotoxicity, and chemotactic activity and has been widely used as a marker of lipid peroxidation.[1][2][3] 4-oxo-2-Nonenal is a more recently identified product of lipid peroxidation.[4][5][6] It actively modifies histidine and lysine residues on proteins and causes protein cross-linking. [7][8] 4-oxo-2-Nonenal also modifies 2'-deoxyguanosine, further implicating lipid peroxidation in mutagenesis and carcinogenesis.[4]
Smiles
CCCCCC(=O)\C=C\C=O
Molecular Formula
C9H14O2
Molecular Weight
154.209
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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sc-202020A4-Oxo-2-nonenal
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