POV-PC

• Target:

  Apoptosis

• Related Pathways:

  Apoptosis

• Bioactivity:

  POV-PC is an oxidized phospholipid that inhibits VSMC growth under high serum conditions and induces apoptosis under low serum conditions. POVPC reduces NO production and expression of CD31 and endothelial NOS, triggering ferroptosis in vascular smooth muscle cells, promoting vascular calcification.

• Smiles:

  [C@H](COP(OCC[N+](C)(C)C)(=O)[O-])(COC(CCCCCCCCCCCCCCC)=O)OC(CCCC=O)=O

• Molecular Formula:

  C29H56NO9P

• Molecular Weight:

  593.73

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  121324-31-0