Propargylcholine (bromide)

CAT: 0804-HY-129084-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-129084-01Size:5 mg
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AVAILABILITY: InStock
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Description
Propargylcholine bromide is a choline analogue containing terminal propargyl that can be incorporated into all classes of Choline-containing phospholipids such as phosphatidylcholine and sphingomyelin, labeling Choline-containing phospholipids. Propargylcholine bromide-labeled phospholipid molecules can be visualized in cells with high sensitivity and spatial resolution. Propargylcholine bromide can be used as a molecular tool to study the biochemical and metabolic processes of Choline-containing phospholipids in cells[1][2]. Propargylcholine (bromide) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
CAS Number
[111755-76-1]
UNSPSC
12352211
Hazard Statement
H315, H319, H335
Target
Biochemical Assay Reagents
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/propargylcholine-bromide.html
Purity
99.97
Solubility
DMSO : 125 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
Smiles
C#CC[N+](C)(CCO)C.[Br-]
Molecular Formula
C7H14BrNO
Molecular Weight
208.10
Precautions
H315, H319, H335
References & Citations
[1]Jao CY, et al. Metabolic labeling and direct imaging of choline phospholipids in vivo. Proc Natl Acad Sci U S A. 2009 Sep 8;106 (36) :15332-7. |[2]Karen R. Bottenfield, et al. Optimization of Propargylcholine to Label Newly Synthesized Myelin in the Rhesus Monkey Brain. FASEB J. 2020, 34 (S1) : 1-1.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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