Galactosylcerebrosides (hydroxy)

• Target:

  Others

• Related Pathways:

  Others

• Bioactivity:

  Galactosylcerebrosides are glycosphingolipids that contain a galactose attached to a ceramide acylated with a hydroxy or non-hydroxy fatty acid. They are metabolic precursors to sulfatides , found primarily in nerve tissues, and are the main glycosphingolipids in the central nervous system. Galactosylcerebrosides are involved in a multitude of cellular processes including cell agglutination, cellular signaling in glycosynapses, cellular development, and activation of T cells. They accumulate in globoid cells in the brain of patients with Krabbe disease, a disorder characterized by a deficiency in galactosylcerebrosidase activity. This product is a mixture of isolated bovine hydroxy galactosylcerebrosides.

• Smiles:

  O[C@H]1[C@@H](O)[C@@H](CO)O[C@@H](OC[C@H](NC(C(O)[R])=O)[C@H](O)/C=C/CCCCCCCCCCCCC)[C@@H]1O

• Molecular Formula:

  C42H81NO9 (for 2-hydroxy Stearoyl)

• Molecular Weight:

  744.1

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  37211-11-3