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VU0486321

CAT: 0931-T35081-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T35081-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1816301-67-3
Target
Others, GluR
Related Pathways
Neuroscience, Others
Bioactivity
VU0486321 is a potent mGlu1 PAM with moderate rat PK (CLp = 13.3. mL/min/kg, t1/2 = 54 min), good free fraction (human fu = 0.05, rat fu =0.03) and excellent CNS penetration (Kp = 1.02) .
Smiles
O=C1N(C(=O)C=2C1=C(F)C=CC2)C3=C(Cl)C=C(NC(=O)C4=C(C)C=CO4)C=C3
Molecular Formula
C20H12ClFN2O4
Molecular Weight
398.77
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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