Vesnarinone

CAT: 0931-T3465-01Size: 2 mgDry Ice: NoHazardous: No

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CAT#:0931-T3465-01Size:2 mg

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CAS Number

81840-15-5

Target

HIV Protease, PDE

Related Pathways

Microbiology/Virology, Metabolism, Proteases/Proteasome

Purity

0.9875

Bioactivity

Vesnarinone (Arkin) (INN) is a mixed phosphodiesterase 3 inhibitor and ion-channel modifier that has modest, dose-dependent, positive inotropic activity, but minimal negative chronotropic activity. It also suppresses cell proliferation and induces apoptosis by inducing the expression of p21, an inhibitor of cyclin-dependent kinase activity in p53-mediated cell cycle arrest.

Smiles

COc1ccc(cc1OC)C(=O)N1CCN(CC1)c1ccc2NC(=O)CCc2c1

Molecular Formula

C22H25N3O4

Molecular Weight

395.45

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Chemical Information

Vesnarinone

Arkin (TN) is an organic molecular entity.

CAS Number	81840-15-5
PubChem CID	5663
IUPAC Name	6-[4-(3,4-dimethoxybenzoyl)piperazin-1-yl]-3,4-dihydro-1H-quinolin-2-one
Molecular Formula	C22H25N3O4
Molecular Weight	395.5
XLogP	2.1
Topological Polar Surface Area	71.1
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	4
Heavy Atom Count	29
Formal Charge	0
Complexity	593

SMILES

COC1=C(C=C(C=C1)C(=O)N2CCN(CC2)C3=CC4=C(C=C3)NC(=O)CC4)OC

InChI

InChI=1S/C22H25N3O4/c1-28-19-7-3-16(14-20(19)29-2)22(27)25-11-9-24(10-12-25)17-5-6-18-15(13-17)4-8-21(26)23-18/h3,5-7,13-14H,4,8-12H2,1-2H3,(H,23,26)

InChIKey

ZVNYJIZDIRKMBF-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 81840-15-5

CID: 5663

Formula: C22H25N3O4

MW: 395.5

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	395.5
XLogP3	2.1
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	4
Exact Mass	395.18450629
Monoisotopic Mass	395.18450629
Topological Polar Surface Area	71.1 Å²
Heavy Atom Count	29
Formal Charge	0
Complexity	593
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Alternative Products

Catalog	Name
BUP16252-01	Vesnarinone
MBS5802429	Vesnarinone HCl
A13313-200	Vesnarinone 200mg
A13313-2	Vesnarinone 2mg
HY-15297R-01	Vesnarinone (Standard)
A13313-50	Vesnarinone 50mg

Vesnarinone

Chemical Information

Alternative Products

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