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Piromelatine

CAT: 0931-T34081-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T34081-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
946846-83-9
Target
Melatonin Receptor, 5-HT Receptor, P2X Receptor, MT Receptor, Sodium Channel, TRP/TRPV Channel
Related Pathways
Neuroscience, GPCR/G Protein, Membrane transporter/Ion channel
Purity
>99.99%
Bioactivity
Piromelatine is an agonist of melatonin MT1/MT2 receptors, 5-HT1A and 5-HT1D, and an antagonist of 5-HT2B.Piromelatine has antinociceptive activity with inhibitory effects on P2X3, TRPV1, and Nav1.7 channels, and can be used in studies of sleep-promoting, pain-relieving, anti-neurodegenerative, and antidepressant diseases. diseases, and can be used to improve memory deficits associated with chronic mild stress-induced lack of pleasure in rats.
Smiles
COc1ccc2[nH]cc(CCNC(=O)c3cc(=O)cco3)c2c1
Molecular Formula
C17H16N2O4
Molecular Weight
312.32
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
BA5026-25Piromelatine
HY-105285R-01Piromelatine (Standard)

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