Niraparib

• Target:

  PARP|||Apoptosis

• Related Pathways:

  Apoptosis|||DNA Damage/DNA Repair|||Chromatin/Epigenetic

• Purity:

  0.9991

• Bioactivity:

  Niraparib (MK-4827) is a PARP inhibitor that selectively targets PARP1 and PARP2 (IC50=3.8/2.1 nM), exhibiting antitumor activity, inhibiting DNA damage repair, and inducing apoptosis.

• Smiles:

  C(N)(=O)C=1C=2C(=CN(N2)C3=CC=C(C=C3)[C@@H]4CCCNC4)C=CC1

• Molecular Formula:

  C19H20N4O

• Molecular Weight:

  320.39

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1038915-60-4