Niraparib

CAT: 0931-T3231-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-T3231-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1038915-60-4
Target
PARP|||Apoptosis
Related Pathways
Apoptosis|||DNA Damage/DNA Repair|||Chromatin/Epigenetic
Purity
0.9991
Bioactivity
Niraparib (MK-4827) is a PARP inhibitor that selectively targets PARP1 and PARP2 (IC50=3.8/2.1 nM), exhibiting antitumor activity, inhibiting DNA damage repair, and inducing apoptosis.
Smiles
C(N)(=O)C=1C=2C(=CN(N2)C3=CC=C(C=C3)[C@@H]4CCCNC4)C=CC1
Molecular Formula
C19H20N4O
Molecular Weight
320.39
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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