Products for Research Use Only
RegisterLogin

MK-571 sodium

CAT: 0931-T3148-01Size: 2 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T3148-01Size:2 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
115103-85-0
Target
LTR, Leukotriene Receptor, LPL Receptor, P-gp
Related Pathways
GPCR/G Protein, Immunology/Inflammation, Membrane transporter/Ion channel, Neuroscience
Purity
0.9958
Bioactivity
MK-571 sodium (L-660711 sodium salt) is a selective, orally active antagonist of the CysLT1 receptor. MK-571 sodium is a multidrug resistance protein-2 (ABCC2, Mrp2) inhibitor used to demonstrate the role of Mrp2 in the cellular efflux of drugs, xenobiotics, and their conjugates. MK-571 sodium can inhibit the synthesis of K-4′-O-GlcA (19.7 μM) . MK571 dose-dependently inhibits the intracellular biosynthesis of all flavonol sulphates and glucuronides by Caco-2 cells. MK-571 sodium significantly inhibits phase-2 conjugation of kaempferol by cell-free extracts of Caco-2, and production of kaempferol-4′-O-glucuronide was competitively inhibited. In addition to inhibiting MRP2, MK571 is a potent inhibitor of enterocyte phase-2 conjugation.
Smiles
[Na+].CN(C)C(=O)CCSC(SCCC([O-])=O)c1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1
Molecular Formula
C26H27ClN2O3S2·Na
Molecular Weight
537.07
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Related Products

CatalogName
T7841-01MK 571
T33424L-01MK-0952 Sodium
T2625L-01MK-0752 Sodium
T71309-01MK-886 sodium salt
T12060-01MK-2894 sodium salt
T27822LFF 571
T9901A-974-01MK-4721
T9901A-857-01MK-4166
T2126-01MK-5046
T16089-01MK-0674

Alternative Products

CatalogName
522669MK-571 sodium
HY-19989A-01MK-571 (sodium)
MBS5756866-01MK-571 sodium salt
BML-RA109-0025MK-571 . sodium salt
A15983-25MK-571 sodium salt 25mg
A15983-10MK-571 sodium salt 10mg
sc-218859MK-571-d6 Sodium Salt
B8031-10MK-571 sodium salt hydrate

Popular Products