CG0009

CAT: 0931-T30807-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T30807-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

944744-57-4

Target

Others

Related Pathways

Others

Bioactivity

CG0009 is a potent and highly selective glycogen synthase kinase 3 (GSK3) inhibitor that inhibitions proliferation, induces apoptosis, and activates the p53-Bax pathway in breast cancer cells through cyclin D1 depletion. CG0009 inhibit breast cancer cell growth through cyclin D1 depletion and p53 activation, and thus may provide an innovative treatment approach for breast cancer resistant to hormone-based therapies.

Smiles

C(NC=1C(C)=CC=NC1)(=O)C2=C3C(N=C(N3)C4=CC=C(N(CCN(CC)CC)C)C=C4)=NC=C2

Molecular Formula

C26H31N7O

Molecular Weight

457.57

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Chemical Information

2-[4-[2-(diethylamino)ethyl-methylamino]phenyl]-N-(4-methyl-3-pyridinyl)-1H-imidazo[4,5-b]pyridine-7-carboxamide

CAS Number	944744-57-4
PubChem CID	57766944
IUPAC Name	2-[4-[2-(diethylamino)ethyl-methylamino]phenyl]-N-(4-methyl-3-pyridinyl)-1H-imidazo[4,5-b]pyridine-7-carboxamide
Molecular Formula	C26H31N7O
Molecular Weight	457.6
XLogP	3.4
Topological Polar Surface Area	90
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	9
Heavy Atom Count	34
Formal Charge	0
Complexity	637

SMILES

CCN(CC)CCN(C)C1=CC=C(C=C1)C2=NC3=NC=CC(=C3N2)C(=O)NC4=C(C=CN=C4)C

InChI

InChI=1S/C26H31N7O/c1-5-33(6-2)16-15-32(4)20-9-7-19(8-10-20)24-30-23-21(12-14-28-25(23)31-24)26(34)29-22-17-27-13-11-18(22)3/h7-14,17H,5-6,15-16H2,1-4H3,(H,29,34)(H,28,30,31)

InChIKey

PFCCDXDYVNKMHB-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 944744-57-4

CID: 57766944

Formula: C26H31N7O

MW: 457.6

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	457.6
XLogP3	3.4
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	9
Exact Mass	457.25900864
Monoisotopic Mass	457.25900864
Topological Polar Surface Area	90 Å²
Heavy Atom Count	34
Formal Charge	0
Complexity	637
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Alternative Products

Catalog	Name
GTR19195169-01	CG0009

CG0009

Chemical Information

Alternative Products

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