WB403

CAT: 0931-T29154-01Size: 100 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0931-T29154-01Size:100 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

CAS Number

1594041-84-5

Target

Others, GPCR19

Related Pathways

Others, GPCR/G Protein

Bioactivity

WB403 is a TGR5 activator. WB403 significantly decreases fasting blood glucose, postprandial blood glucose and HbA1c, improves glucose tolerance in type 2 diabetic mice. WB403 increases pancreatic β-cells and restores the normal distribution pattern of α-cell and β-cell in islets.

Smiles

C(OCC1=CC=C(Br)C=C1)C=2SC(=NC2C)C=3C=C(CC)N=CC3

Molecular Formula

C19H19BrN2OS

Molecular Weight

403.34

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Chemical Information

5-[(4-Bromophenyl)methoxymethyl]-2-(2-ethyl-4-pyridinyl)-4-methyl-1,3-thiazole

CAS Number	1594041-84-5
PubChem CID	86301970
IUPAC Name	5-[(4-bromophenyl)methoxymethyl]-2-(2-ethyl-4-pyridinyl)-4-methyl-1,3-thiazole
Molecular Formula	C19H19BrN2OS
Molecular Weight	403.3
XLogP	4.6
Topological Polar Surface Area	63.3
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	6
Heavy Atom Count	24
Formal Charge	0
Complexity	378

SMILES

CCC1=NC=CC(=C1)C2=NC(=C(S2)COCC3=CC=C(C=C3)Br)C

InChI

InChI=1S/C19H19BrN2OS/c1-3-17-10-15(8-9-21-17)19-22-13(2)18(24-19)12-23-11-14-4-6-16(20)7-5-14/h4-10H,3,11-12H2,1-2H3

InChIKey

NYKBJEUCSJOODJ-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 1594041-84-5

CID: 86301970

Formula: C19H19BrN2OS

MW: 403.3

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	403.3
XLogP3	4.6
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	6
Exact Mass	402.04015
Monoisotopic Mass	402.04015
Topological Polar Surface Area	63.3 Å²
Heavy Atom Count	24
Formal Charge	0
Complexity	378
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Alternative Products

Catalog	Name
GTR19196155-01	WB403

WB403

Chemical Information

Alternative Products

Popular Products