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UK-122 TFA salt

CAT: 0931-T29051-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T29051-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1186653-73-5
Target
Others, PAI-1
Related Pathways
Others, Metabolism
Bioactivity
UK-122 is a potent and selective uPA inhibitor (Ki = 20 nM) . The IC (50) of UK122 in a cell-free indirect uPA assay is 0.2 micromol/L. UK122 showed little cytotoxicity against CFPAC-1 cells (IC (50) > 100 micromol/L) but significantly inhibited the migration and invasion of this pancreatic cancer cell line.
Smiles
C(C(O)=O)(F)(F)F.C(=C\1/N=C(OC1=O)C2=CC=CC=C2)\C3=CC=C(C(=N)N)C=C3
Molecular Formula
C19H14F3N3O4
Molecular Weight
405.33
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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