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MPT0B206

CAT: 0931-T28092-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T28092-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Others
Related Pathways
Others
Bioactivity
MPT0B206 is a novel tubulin polymerization inhibitor. MPT0B206 induced G2/M cell cycle arrest and the appearance of the mitotic marker MPM-2 in K562 and K562R cells, which is associated with the upregulation of cyclin B1 and the dephosphorylation of Cdc2. Treatment of K562 and K562R cells with MPT0B206 induced apoptosis and reduced the protein levels of procaspase-9 and procaspase-3 and increased caspase-3 activity and PARP cleavage.
Smiles
O=CNC1=CC=CC2=C1N(S(=O)(C3=CC=C(OC)C=C3)=O)CC2
Molecular Formula
C16H16N2O4S
Molecular Weight
332.37
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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