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MMRi64

CAT: 0931-T28078-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T28078-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
430458-66-5
Target
P53, MDM-2/p53, Apoptosis, Mdm2
Related Pathways
Apoptosis
Purity
0.9993
Bioactivity
MMRi64 is a specific inhibitor of Mdm2-MdmX E3 ligase activity.MMRi64 potently induces p53 accumulation and apoptosis in the p53 pathway in leukemia/lymphoma cells, disrupts Mdm2-MdmX interactions, and downregulates Mdm2 and MdmX in leukemia cells.MMRi64 MMRi64 can be used in cancer research.
Smiles
C(NC1=CC(C)=CC=N1)(C2=C(O)C3=C(C=C2)C=CC=N3)C4=C(Cl)C(Cl)=CC=C4
Molecular Formula
C22H17Cl2N3O
Molecular Weight
410.3
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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