Avasimibe

• Target:

  Cytochromes P450|||Acyltransferase

• Related Pathways:

  Metabolism

• Purity:

  0.9991

• Bioactivity:

  Avasimibe (PD-148515) is an orally bioavailable inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT, IC50: 3.3 ?M) that prevents cholesterol deposition in the arterial wall. It also inhibits human P450 isoenzymes CYP2C9/1A2/2C19 (IC50: 2.9/13.9/26.5 ?M) .

• Smiles:

  CC(C)c1cc(C(C)C)c(CC(=O)NS(=O)(=O)Oc2c(cccc2C(C)C)C(C)C)c(c1)C(C)C

• Molecular Formula:

  C29H43NO4S

• Molecular Weight:

  501.72

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  166518-60-1