Avasimibe

CAT: 0931-T2753-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T2753-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

166518-60-1

Target

Cytochromes P450, Acyltransferase

Related Pathways

Metabolism

Purity

0.9991

Bioactivity

Avasimibe (PD-148515) is an orally bioavailable inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT, IC50: 3.3 μM) that prevents cholesterol deposition in the arterial wall. It also inhibits human P450 isoenzymes CYP2C9/1A2/2C19 (IC50: 2.9/13.9/26.5 μM) .

Smiles

CC(C)c1cc(C(C)C)c(CC(=O)NS(=O)(=O)Oc2c(cccc2C(C)C)C(C)C)c(c1)C(C)C

Molecular Formula

C29H43NO4S

Molecular Weight

501.72

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Alternative Products

Catalog	Name
A4318-200	Avasimibe

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