Avasimibe

• Target :

  Cytochromes P450|||Acyltransferase

• Related Pathways :

  Metabolism

• Purity :

  0.9991

• Bioactivity :

  Avasimibe (PD-148515) is an orally bioavailable inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT, IC50: 3.3 ?M) that prevents cholesterol deposition in the arterial wall. It also inhibits human P450 isoenzymes CYP2C9/1A2/2C19 (IC50: 2.9/13.9/26.5 ?M) .

• Smiles :

  CC(C)c1cc(C(C)C)c(CC(=O)NS(=O)(=O)Oc2c(cccc2C(C)C)C(C)C)c(c1)C(C)C

• Molecular Formula :

  C29H43NO4S

• Molecular Weight :

  501.72

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  166518-60-1